In addition to more standard CVD risk factors, we also measured four inflammatory markers (TNF-αR2, P-selectin, ICAM-1, and hs-CRP) that have been associated either with excess adiposity and atherosclerosis in animal and autopsy studies, pre-clinical vascular testing and as predictors of adult cardiovascular disease events [18]. The gene discussed is ICAM1; the disease is atherosclerosis.