INS and Insulin resistance: It is important to point out that with our study we cannot rule out that, in addition to the change in amount and type of protein, the presence of other components of the diet such as the amount of carbohydrates, fat and dietary fiber could directly impact glucose levels, insulin signaling or insulin secretion; for example, the urban diet has a higher proportion of simple carbohydrates, which have a higher insulinemic and glycemic index that can per se contribute to the development of insulin resistance.