SQSTM1 and HIV infectious disease: Although the microarray and qRT-PCR data did not correlate for the genes we had examined up to this point, most likely due to the particular tissue sample subset we used, at the transcriptional level the combined results suggest that autophagic processes may differ in a brain region-specific manner during HIV infection, more closely associated with the NCI-HIVE condition, with higher activity in the basal ganglia as indicated by LAMP1 levels from the microarray data and lower activity in the frontal lobe white matter and frontal cortex as indicated by SQSTM1 levels using qRT-PCR.