Nuclear receptors have also been noted as having tumor suppressive functions including VDR’s protective function in colon cancer (16); PPARg’s activation in reducing tumorigenicity in many cancer tissue types (17); TR4 and RARb as tumor suppressors in prostate (18, 19), and NUR77 and NOR1 as tumor suppressors in AML (20). The gene discussed is RARB; the disease is neoplasm.