LGALS3 and heart failure: Biomarkers related to fibrosis, such as N-terminal propeptide of type I and III procollagens (PINP and PIIINP, respectively), galectin-3 (gal-3), and soluble ST2 protein (ST2) have been associated with poor outcome among heart failure patients (Cicoira et al., 2004; Pascual-Figal et al., 2009; Velagaleti et al., 2010; De Boer et al., 2011; Bayes-Genis et al., 2012; Lok et al., 2013).