LRRK2 and Parkinson disease: Additionally, activated microglia have been found in the SNpc and in the striatum of PD animal models (Pisanu et al., 2014; Stott and Barker, 2014) and have been associated with different PD-associated gene/proteins like α-syn or LRRK2 (Daher et al., 2014; Sacino et al., 2014).