GPT and Sepsis: It must be noted that comparison of those two experimental setups (i.e. CLP-Only and CLP-ODam) is not ideal considering the dissimilar release mechanism of the measured biomarkers: pronounced hepatocyte (cirrhotic) necrosis caused ALT/LDH secretion in CLP-ODam mice [26], while their release in sepsis (i.e. CLP-Only) can be attributed to circulatory disturbances (e.g. decreased arterial hepatic blood flow) rather than necrosis/apoptosis [1].