To adjust for potential cofounding covariates, and including only covariates with greater than 90% data completeness in TCGA datasets for DNA BD MMs cases, multiple multivariate Cox proportional-hazards regression models were tested for covariates age, surgical stage, histologic grade, TP53 CNA, TP53 mRNA expression level, and total number of tumor mutations to determine the best regression model. The gene discussed is TP53; the disease is neoplasm.