Additionally, no significant differences in OS or PFS were observed by KM analysis of all or optimally cytoreduced DNA BD MM cases classified by mutation type, secondary structure, TP53 CNA, truncating versus non-truncating mutations, or among the six most frequently observed hotspot MMs in TCGA cases (Supplementary Table 2), consistent with analyzes previously reported [8]. This evidence concerns the gene TP53 and Miyoshi myopathy.