JAG1 and Carcinoma, Lewis Lung: With this purpose, we have fully characterized tumor growth and progression, and the associated vascular phenotype and cellular metabolic consequences in endothelial Jag1 mutants in two different mouse tumor models: subcutaneous Lewis Lung Carcinoma (LLC) tumor transplants and in the autochthonous transgenic adenocarcinoma of the mouse prostate (TRAMP) [16, 17].