Cystic fibrosis (CF) is a genetic disorder caused by mutations in the CFTR gene, resulting in a multisystem disease dominated by pulmonary symptoms and the establishment of chronic pulmonary infections with bacteria, e.g. Staphylococcus aureus, Haemophilus influenzae, and Pseudomonas aeruginosa. The gene discussed is CFTR; the disease is cystic fibrosis.