APOB and coronary atherosclerosis: Finally, due to lack of clinical data, we have not examined the effects of SNPs and the GRS on more biomarkers such as lipoprotein (a), apolipoprotein A1 and apolipoprotein B, and on imaging measures, such as the extent of coronary atherosclerosis (the Sullivan Extent scores) and carotid intima-media thickness (CIMT).