Furthermore, to investigate whether overexpression of IL13Rα2 is involved in breast cancer metastasis, we performed in vivo metastasis assays by injecting MIV-Luc-shSCR or MIV-Luc-shIL13Rα2#2 cells via the lateral tail vein of NOD/SCID mice and quantified photon flux weekly by bioluminescence imaging. The gene discussed is IL13RA2; the disease is breast cancer.