Chen et al. reported a significantly higher mRNA and protein expression of Cdc7 in 39 colorectal cancers as compared to tumor-adjacent normal colorectal tissue [18] and colorectal cancer is among the cancer types that shows the strongest up regulation in Cdc7 expression as determined from data obtained by mining Oncomine and Gene Expression Omnibus databases. The gene discussed is CDC7; the disease is colorectal cancer.