LARGE1 and cancer: Besides the multiple LOH- or GOH-bearing cancer-related genes detected, a host of other genes from the Ensembl database that were unlisted in either TSGene or NCG4.0 also underwent LOH and GOH mutations (Additional file 9: Tables S7E-F), and those unlisted genes that displayed highest occurrences of LOH or GOH, or in the largest numbers of cancer samples, are shown in Tables 2E-F, e.g. FRMD4A with fourteen LOHs, CAMK1D with 12 LOHs and 14 GOHs, AFAP1 with twelve GOHs, and LARGE with eleven GOHs.