Significant difference in ZFPM2 expression between the two genotype subgroups was observed for astrocytomas (n = 38, P = 0.028) as determined using Student’s t-test, with lower expression in the homozygous group, but no difference was found for oligodendroglial tumors (n = 31, P = 0.347) (Fig 4C). This evidence concerns the gene ZFPM2 and astrocytoma (excluding glioblastoma).