However, scrib- + NACT + bskDN clones also exhibited elevated Hth levels indicating that the upregulation was not JNK-dependent (S3D Fig); and expressing NACT in scrib-hth- double mutant clones still elicited the formation of large invasive tumors throughout an extended larval stage, indicating that Hth was not absolutely required for tumor overgrowth (S3F Fig). Here, SCRIB is linked to neoplasm.