Other tumor growth promoting pathways are also likely to be activated by JNK, since JNK can promote the expression of morphogens such as Dpp (TGFβ-like) and Wingless (the Drosophila Wnt ligand) [27], as well as increase the activity of the Hippo pathway transducer, Yorkie (Yki) [28], which is required for tumor overgrowth [29]. Here, MAPK8 is linked to neoplasm.