In the scrib- + RasV12 tumors, JNK-positive tumor cells with mesenchymal-like morphology are observed at the invasive front [16], and transcriptional targets of JNK in the tumors include genes required for invasion, such as Matrix metalloproteinase 1 (Mmp1), Paxillin (Pax) [16, 21], and the Filamin, cherio (cher) [23]. This evidence concerns the gene MAPK8 and neoplasm.