However, consistent with the array data, Ab did not appear to be a JNK–induced gene, since Ab levels were not increased in all msn-lacZ positive tumor cells, and ectopically activating JNK signaling within eye disc clones by expressing an activated allele of JNKK, hepACT, did not lead to increased levels of Ab (S7 Fig). Here, MAP2K4 is linked to neoplasm.