SCRIB and breast neoplasm: Interestingly, we recently identified dl in an overexpression screen for genes capable of cooperating with scrib- in Drosophila tumorigenesis [69], and Mef2 has been identified as a cooperating oncogene in Drosophila, and possibly also in humans, where a correlation exists between the expression of Notch and Mef2 paralogues in human breast tumor samples [87].