Among the top genes are ones that have been previously related to asthma (e.g., APOE [20], CHI3L1 [21], EGR1 [22], MYH11 [23], OXTR [24], SERPINB2 [25,26], SOCS3 [27]) and corticosteroid-resistant asthma (e.g., FOS [28]) though not necessarily in humans or via changes of the ASM. The gene discussed is EGR1; the disease is asthma.