The multivariate analysis of significant factors identified in the univariate analyses (tumor size, lymph node metastases, histological type, extent of tumor invasion, lymphovascular invasion, adjuvant chemotherapy and PgR), in addition to age and YFLC, showed the independent prognostic facers to be the number of lymph node metastases (4–9, HR:3.388, 95% CI 1.363–8.425, p = 0.0086, over 10, HR: 6.714, 2.033–22.177, p = 0.0018), solid-tubular carcinoma (HR 3.348, 1.352–8.292, p = 0.0090), scirrhous carcinoma (HR 2.294, 1.013–5.197, p = 0.0465) and past YFLC (HR 0.422, 0.186–0.956, p = 0.0387. The gene discussed is PGR; the disease is scirrhous adenocarcinoma.