DCC and cancer: On the other hand, DCC alterations were constantly observed with a high frequency in all TNM stages; hence, DCC alterations were found in 63 % (10/16 informative cases), 76 % (19/25 informative cases), 66 % (19/29 informative cases), and 77 % (10/13 informative cases) of stages I, II, III, and IV cancers, respectively (Table 2).