LTβR signalling is well known to recruit lymphoid and myeloid cells into lymphoid organs and tumours,47, 48 and activation mediates accumulation of macrophages and NKT/T cells in association with increased expression of CXCL10 and CCL2 in AKT/CAT and AKT/NICD tumours (online supplementary figure 11 A, B). This evidence concerns the gene LTBR and neoplasm.