Moribund livers following 8 weeks of anti-LTβR or Ig treatment displayed a preponderance of lipogenic foci with mean histological scores of 3.7 for anti-LTβR and 3.5 for Ig (figure 3E) and similar incidence of hepatoblastoma/HCC-like tumours following agonism (figure 3E). The gene discussed is LTBR; the disease is hepatoblastoma.