KIR2DS4 gene, without determining full-length versus deleted variants, was found protective against HCV infection, elevated ALT levels and cirrhosis in Argentinian Caucasians (Paladino et al. 2007) and in exposed intravenous drug users of Puerto Rican descent (Zúñiga et al. 2009). Here, KIR2DS4 is linked to Cirrhosis.