TAP1 and cancer: Only TAP1 D637G polymorphism was found to be associated with cancer risk, which was significantly increased for carriers of at least one G allele (OR, 1.659; 95 % CI, 1.112–2.474) and heterozygote carriers of the variant allele G (OR, 1.626; 95 % CI, 1.080–2.449) (Table 4).