MEG3 and hydrops fetalis: Since MEG3 lncRNA was identified as a repressive chromatin-associated RNAin the ChRIP analysis (Fig. 1d,e), and also as one of thechromatin-interacting RNAs in our previous study involving sucrose-fractionatedchromatin from normal human fibroblasts (HF cells)28, we wereinterested in exploring plausible mechanisms by which MEG3 lncRNArecognizes its target genes.