In agreement with our findings, Gonzalez et al. found the MCM2 labelling index to be significantly associated with overall survival and disease free survival in breast cancer and, indeed, that MCM2 was independent of, and superior to, histological grade, Ki67 labelling index and lymph node stage in determining prognosis in a multivariable analysis [20]. The gene discussed is MKI67; the disease is breast carcinoma.