It has been demonstrated that miR-182 overexpression promotes prostate cancer cell proliferation and invasion by targeting multiple genes, including FOXF2 (forkhead box F2), RECK (reversion-inducing-cysteine-rich protein with kazal motifs), MTSS1 (metastasis suppressor 1), and NDRG1 (N-myc downstream regulated 1)28, 29. Here, FOXF2 is linked to Familial prostate cancer.