EEF2 and early-onset autosomal dominant Alzheimer disease: For instance, thymosin-beta (significantly expressed, p < 0.01; Fig. 4a) and EF-2 (significantly expressed; p < 0.05; Fig. 4b) have been associated with important roles in the regulation of neurite outgrowth as well as neuroprotective actions in Alzheimer's disease [71–74].