TGFβ1 is a potent inhibitor of myogenic differentiation and as rhabdomyosarcoma essentially is a tumour of failed myogenic differentiation, Sun et al. [114] investigated miRNAs regulating TGFβ1 and found that amongst these, miRNA 450b-5p was regulated through SMADs signalling. Here, TGFB1 is linked to rhabdomyosarcoma.