CDCA7L and infection: While there was no difference in total worm burden at the 8 week timepoint between mice treated with HR1 antagonists for 10 days and untreated mice (mean worm burden of 17 vs 20), mice treated with 10 days of fexofenadine (HR1i) had significantly greater numbers of adult worms that were encased in granulomas (Fig 3D) at 56 days post infection.