ERBB2 and chronic myelogenous leukemia, BCR-ABL1 positive: Some of the well-established examples on oncogene addiction include amplification of HER2 in breast cancer [27], mutated EGFR in non-small cell lung cancer [28], mutated BRAF in melanomas [29] and Bcr-Abl in chronic myeloid leukemia [30, 31].