Members of the FGFR family (FGFR1 to 4) are key mediators of both developmental anddisease-associated angiogenesis13 and are heavily implicated in thepathogenesis of tumour vascularization in a number of different tumour types includingbreast14, pancreatic15, prostate16 andovarian17 carcinomas, as well as being driving oncogenes formalignant transformation in their own right13, 18. This evidence concerns the gene FGFR1 and neoplasm.