Thus, diet duration does not seem to account for the discrepancy between our results and other work in a similar population.13 Hepatic insulin sensitivity remained unchanged in two studies with a similar HF diet as used by us,7, 10 but was shown to decrease in lean men after 11 days of an 83% HF diet.9 FSIVGTT does not differentiate between hepatic and peripheral insulin×sensitivity. Here, INS is linked to hydrops fetalis.