In lipomas 3, 4 and 7 as well as the osteochondrolipoma, exon 3 of HMGA2 was fused to sequences from 18q12.3 (Fig. 3) which in lipomas 4 and 7 and the osteochondrolipoma consisted of the 3′-untranslated region of the SETBP1 gene. The gene discussed is SETBP1; the disease is lipoma.