GYPA and neoplasm: In univariate analyses, extracerebral tumor control (p < 0.001, uncontrolled 6.8 months vs. controlled 12.4 months), response to SRS (p < 0.001, progressive disease 4.3 months vs. stable disease 8.3 months vs. remission 13.3 months), number of BM (linear p = 0.007; grouped p = 0.005, n > 3 8.3 months vs. n = 2–3 5 months vs. n = 1 12.4 months), RPA class (p = 0.027, class 1 37.8 months vs. class 2 8.3 months versus class 3 3.3 months) and ds-GPA (p = 0.011, score 2 5 months vs. score 3 8.8 months vs. score 4 12.4 months, Fig. 3) were prognostic for overall survival (OS).