Interestingly, however, these alleles are also risk factors for SLE 38, which is not in accordance with the well‐established protective role of FcγRIIb against the development of self‐reactive response, as demonstrated in FcγRIIb‐deficient mice of certain strains that spontaneously develop autoimmune disorders 44. The gene discussed is FCGR2B; the disease is autoimmune disease.