In the cross-sectional analyses, the statistical power of the association analyses between the PNPLA3 genotype and the risk for NAFLD or the value of the eGFR was 87% or 87% for all subjects, 61% or 71% for normal weight subjects and 43% or 26% for overweight subjects, respectively. The gene discussed is PNPLA3; the disease is metabolic dysfunction-associated steatotic liver disease.