Increased EoPs have been observed in Th2 cell-mediated asthma and anti-helminth responses (Iwasaki et al., 2005; Yang et al., 2011), however, our study constitutes the first report of chronic EoP accumulation during IL-23-Th17 cell type-mediated immune disease, extending our previous observation of dysregulated hematopoiesis in colitis to the eosinophilic lineage. This evidence concerns the gene IL37 and immune system disorder.