As shown in Figure 4, we found that anti-Hsp20 antibodies, but not the IgG control, specifically coimmunoprecipitated Bax, suggesting that Bax interacted with Hsp20 in N2a cells, which is in consistency with the results in human hepatocellular carcinoma cells [18]. This evidence concerns the gene HSPB6 and hepatocellular carcinoma.