HLA-C and hepatocellular carcinoma: During DENV infection, the activation of NF-κB has been widely reported to activate apoptosis in neuroblastoma, hepatoma, and endothelial cells [16, 19, 27], accompanied by chemokine production in endothelial cells [17], IL-8 production in monocytes, epithelial cells, and endothelial cells [24], MHC production in hepatoma cells [28], and type I IFN response in lung epithelial cells [29].