Each miRNA could have multiple target genes [15,25]; indeed, several target genes have been predicted and some tested for miR-146, including those that encode the transcription factors NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells), BRMS1 (breast cancer metastasis-suppressor 1) and LPS (Lipopolysaccharides), as well as components of the FGF signalling pathway [26–28]. Here, NFKB1 is linked to breast cancer.