Sequence analysis of genomic DNA demonstrated that RT4, T24, T24-X, RT112 and TCCSUP do not contain the B-RafV600E and K-RasG13D mutant alleles (Fig. 6a, Additional file 4: Figure S4 and Additional file 10: Table S2), thus uncoupling bladder cancer cell susceptibility to 3-BrPA from B-RafV600E and/or K-RasG13D oncogenic functions, contrary to findings of a previous report in colorectal carcinoma [51]. Here, PPIB is linked to urinary bladder carcinoma.