KLLN and renal cell carcinoma: In a panel of eight RCC cell lines (RC-6, RC-9, RC-13, RC-45, 786-O, ACHN, CAKI-1, and CAKI-2) and one normal kidney cell line HEK293T examined for KILLIN promoter methylation, 100 % of the RCC cell lines showed methylation in at least one of the four CpG regions identified whereas HEK293T was completely unmethylated.