NSDvs. OSA p = 0.003 NSD vs. INS p < 0.0001 INS vs. PLM p = 0.002 OSA vs. PLM p = 0.042 NSD vs. PLM p = 0.210 OSA vs. INS p = 0.804. The gene discussed is INS; the disease is obstructive sleep apnea syndrome.