Schuerholz and collaborators showed that, after induction of sepsis in the mouse model of cecal ligation and puncture (CLP), administration of Pep19-2.5 led to marked reduction of CD14 expression in various tissues and to diminished IL-6 as well as IL-1 levels in plasma after 24 h, compared to the untreated control group. Here, IL6 is linked to Sepsis.