CTNNB1 and cancer: CTNNB1 is studied most intensively in colorectal and hepatocellular cancer but has also been described in other cancer types, such as ovarian and endometrial cancer.[51,52] In cervical cancer, CTNNB1 mutations have been detected in 3 out of 15 SCC cell lines,[53,54] but the mutations have never been described in association with survival.