CCR4 and myeloid sarcoma: In addition, mRNA expression of chemokine receptors, such as chemokine (C-X-C motif) receptor 3 (CXCR3), C-C chemokine receptor type 2 (CCR2), and C-C chemokine receptor type 4 (CCR4), also implicated in MS and EAE pathogenesis [33], are described to play a role in the formation of GME lesions [32].