In total, 160 pediatric ALL patients with 7 main subtypes were enrolled in this study, including t(12;21) (ETV6-RUNX1), t(9;22) (BCR-ABL1), t(1;19) (TCF3-PBX1), MLL rearrangement, T-ALL, hyperdiploid >50, and Others (diploid without chromosomal translocation or fusion gene). Here, RUNX1 is linked to acute lymphoblastic leukemia.