BACE1 and early-onset autosomal dominant Alzheimer disease: The first two documents, both published on May 1st 2014, were WO2014066132 from Eli Lilley [9] and WO2014065434 from Shionogi [10], both specifying BACE1 inhibitors for Alzheimer's disease (6132 used BACE as a synonym for BACE1, UniProt P56817).