Here, we examined the number of MDSCs in HPV 16 infection with normal oral mucous specimens, dysplasia, caner in situ and oropharyngeal cancer using the PE-Cy mouse anti-human CD11b, FITC- mouse anti-human LIN, APC mouse anti-human HLA-DR, PE mouse anti-human CD33. This evidence concerns the gene ITGAM and oropharynx cancer.