EGFR and cancer: For example, the Roche Cobas qPCR platform has FDA approved in vitro diagnostic (IVD) products available for EGFR and BRAF, but the output is limited to either one mutational hotspot (BRAF V600) or mutations in a handful of exons (EGFR exons 18, 19, 20 and 21) and are only approved for specific cancer types [9,10].