Furthermore, salubrinal shows neuroprotective effects in vitro and in vivo against neurotoxic substances considered to be responsible for neurological disorders, such as β-amyloid [40,43,44,45], α-synuclein [46,47], mutant huntingtin protein [48], superoxide dismutase 1 mutant [49], ceramide [50], and kainic acid [51,52]. This evidence concerns the gene SOD1 and nervous system disorder.